Saturday, 15 November 2025 08:35 pm

Naked Mole Rats

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The risk of death increases exponentially with age.
So says the Gompertz-Makeham law, but that’s not always true,
For naked mole rats never reach a geriatric stage,
Unless they do much later than all other rodents do.

The oldest in captivity has died at 39.
A normal mammal of its size could scarcely live to six.
What’s more, the older females still can reproduce just fine.
How do they buck the pattern that biology predicts?

We’ve found that they are very good with DNA repair
And chaperones, the proteins that help other proteins fold.
A change to enzyme cGAS means its presence won’t impair
Genetic damage healing, so the rodents don’t grow old.

That said, there are some markers that result from methylation
To estimate their ages if we look at DNA.
Perhaps these markers point to not decline but preservation.
A sticky acid molecule keeps cancer cells at bay.

Moreover, naked mole rats can resist some types of pain
And live for 18 minutes never taking any breath.
Who knows how many benefits we humans stand to gain
From studying this species or how long we’ll stave off death?
deckardcanine: (Default)
My friends, are you cool with the five-second rule,
Where you eat what you drop on the floor
As long as you’re quick so it won’t make you sick?
Does your threshold take less time or more?

The earliest known variation is shown
In a legend about Genghis Khan,
Who let the food stay there as long as he’d say.
(If you take his advice, you’re far gone.)

A handful of scholars have spent research dollars
To test if the rule is OK.
They couldn’t agree, as the findings they’d see
Were quite mixed; we don’t know to this day.

The food that is wet is more likely to get
Some bacteria coming aboard.
A surface that’s had salmonella is bad;
It’s a risk that I couldn’t afford.

Yet most of the time, with no visible grime,
The five seconds spell minimal risk,
Especially while on a carpet, not tile.
If you’re feeling so lucky, be brisk!
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Saturday, 29 March 2025 11:22 pm

BMI

deckardcanine: (Default)
Adolphe Quetelet was a mid-19th-century
Belgian in multiple scientist fields.
He made an eponymous index in search of
The average man as a social ideal.

This index was not called the body mass index
Till nearly a century after he died.
By then, it was favored for medical usage,
In essence a rough adiposity guide.

In light of its origin, one may well wonder
Why doctors still use BMI to this day.
Indeed, many people have said it’s a poor
Rule of thumb that should really be fading away.

For starters, dividing your weight by the square of
Your height makes no sense if you’re not fully flat,
So tall and short people aren’t fairly assessed,
And it makes no distinction twixt muscle and fat.

What’s more, Quetelet based his formula mostly
On data from soldiers of Scotland and France.
It ought to be different for others, especially
Black folks. Do they get called healthy? Fat chance.

A bunch of alternatives have been proposed.
Quetelet even offered a change of his own.
The “new BMI” has a 2.5 exponent,
Scaled to be close to the mean that we’ve known.

The corpulence, Rohrer’s, or ponderal index
Just swaps out the square for a cube. Fair enough?
But tall people tend to be narrow in frame
Next to short folk. Determining fairness is tough.

The BMI Prime compares actual stats with
The threshold beyond which one’s deemed overweight.
Some doctors will focus on visceral fat,
So they measure the waistline (an obvious trait).

A Body Shape Index includes many factors,
The Surface-based Body Shape Index still more.
The modified body mass index has serum
Albumin involved, but don’t ask me what for.

In short, if you don’t trust the most common method,
There’s plenty to choose from for gauging your risk
Of health problems stemming from excess of fat
(Tho some claim the connection just doesn’t exist).
deckardcanine: (Default)
We all know that spinach won’t give us the muscles
Of Popeye, who’s simply cartoony.
In fact, it’s a poor source of iron; relying
On that would, at best, leave us puny.

For decades, the common assumption has been
That the rumor began with a typo:
Around 1890, a decimal point
Got misplaced. Did this start all the hype? No.

Nutritionists botched it before 1870,
Likely without a stray dot.
They may have made errors in methods, including
Some spinach dried up and some not.

I’ll note we can find as much iron in spinach
Per ounce as we’d find in a steak,
But those who eat spinach absorb a lot less.
Guess the error is easy to make.
Sunday, 18 August 2024 03:42 pm

They Had a Vision

deckardcanine: (Default)
While carrots can bolster the health of your eyes
With a big dose of vitamin A,
They won’t make your vision work better than normal:
You can’t see by night as by day.

So how was the rumor blown out of proportion?
It flourished in World War II,
When ministers claimed British pilots ate carrots
So night raids were easy to do.

Of course, this was mere propaganda; they meant
To divert any German tactician.
We’re not sure it worked, but the public was fooled
Into buying the whole superstition.
deckardcanine: (Default)
The Turritopsis dohrnii, or immortal jellyfish,
Can do what many humans rather seriously wish:
When subject to a sudden drop in temperature or salt
Or starved or greatly damaged, it reverts to its default—
That is, becomes a polyp after something like a cyst
Or else becomes a stolon, and the first stage might be missed.
In time, it forms a colony to bud and then release
Medusae like its grown-up form and thus may not decease.
Genetically identical medusae, more or less,
Are found across the oceans. That’s survival with finesse!
The process of their cells is called transdifferentiation.
It might reveal the secret to our own rejuvenation.
Saturday, 7 August 2021 08:05 pm

Frozen Shoulder

deckardcanine: (Default)
For months, my favored arm has had a smaller range of motion.
At first, I thought this sort of thing just came with getting older,
But now a diagnosis has revised my early notion:
Adhesive capsulitis, also known as frozen shoulder.

I don’t know how it happened; I am hardly diabetic
Or otherwise afflicted, and I never had a stroke.
I haven’t been immobilized; I’ve gotten more athletic.
I haven’t needed surgery, and nothing in me broke.

Whatever got it started, let me “capsulize” the issue:
To move, I need a fluid that will lubricate the joint.
Right now, my shoulder capsule (that’s a strong connective tissue)
Has thickened with adhesions, and it’s harder to anoint.

The good news is, my pain’s decreased; perhaps I’ve finished freezing
And now am in the second stage, with thawing on the way.
I’m going to some therapists, who stand to help with easing
Recovery; already I’ve made progress, so they say.
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Saturday, 12 June 2021 05:38 pm

The Axolotl

deckardcanine: (Default)
The axolotl’s not like other salamander types.
For one, it’s neotenic, so it doesn’t change its stripes;
That is, it keeps its larval traits and stays forever young.
It always lives in water, though it does develop lungs.

In keeping with this constancy, it also can regrow
Most body parts in little time. Just how? We’d like to know,
Especially in light of its superior resistance
To cancer next to mammals’: Could it be of some assistance?

Alas, although it’s popular for keeping as a pet
Or eating in some cultures, it is very hard to get.
In part, it is elusive, but it’s also gotten rare;
It’s critically endangered in the wild, so let’s take care.

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Stephen Gilberg

April 2026

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